Fabrazyme® Infusion Therapy
About Fabrazyme® Infusion Therapy
Fabrazyme® (agalsidase beta) is an FDA-approved enzyme replacement therapy (ERT) used to treat Fabry disease, a rare inherited lysosomal storage disorder. Fabrazyme® works by replacing the deficient or absent alpha-galactosidase A enzyme, helping to reduce the accumulation of globotriaosylceramide (GL-3) in the body's cells.
Condition treated by this therapy
- Fabry disease (confirmed diagnosis)
Fabry disease is a rare X-linked lysosomal storage disorder caused by a deficiency of the enzyme alpha-galactosidase A. This leads to the progressive accumulation of GL-3 in cells throughout the body, affecting the kidneys, heart, nervous system, and skin.
Fabrazyme® is indicated for adult and pediatric patients 2 years of age and older with confirmed Fabry disease. By replacing the deficient enzyme, Fabrazyme® helps clear GL-3 deposits and slow disease progression.
Fabrazyme® Price
The out-of-pocket cost for Fabrazyme® will vary depending on your insurance coverage. If you have questions about your coverage, contact your insurance provider.
Many patients with commercial insurance may qualify for patient assistance programs through Sanofi Genzyme. For those without insurance, financial assistance options may be available. No patient should go without necessary treatment due to financial limitations. Contact a member of our Violet Health team for more information.
What to Expect During Fabrazyme® Infusion Therapy
Fabrazyme® is administered as an intravenous (IV) infusion at a dose of 1 mg/kg every 2 weeks. Premedications including Tylenol 1000mg PO, Benadryl 25mg PO, and Solumedrol may be given prior to infusion. Infusion sessions are conducted in a clinical setting under the supervision of trained healthcare providers who follow established adult rescue management protocols.
Fabrazyme® Side Effects
Some patients may experience infusion-related reactions with Fabrazyme®. Common reactions include fever, chills, rigors, headache, rash, itching, swelling, edema, nausea, vomiting, abdominal pain, hypotension, and respiratory distress. Your provider will monitor you throughout treatment and follow established rescue management protocols if a reaction occurs.
Fabrazyme® Infusion Therapy at Violet Health
Your comfort during Fabrazyme® infusion therapy at Violet Health is our priority. Our patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Violet Health's evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.
Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.
Helpful Resources
Patient Forms
Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!
Meet our Infusion Specialists
Jalal Thwainey M.D.
Medical Director
Emilie Wojcik, N.P.
Director of Clinical Services
For Provider
Simplify patient referrals and offer advanced treatment options with our infusion partnership program.
For Patient
There may be a better way to manage your condition – explore infusion therapy.