About EXDENSUR® Injection Therapy
EXDENSUR® (elapegademase-lvlr) is an enzyme replacement therapy designed to treat adenosine deaminase severe combined immune deficiency (ADA-SCID), a rare and serious genetic condition. To understand how EXDENSUR® works, it's helpful to know about the role of enzymes in your body.
In ADA-SCID, the body lacks a crucial enzyme called adenosine deaminase (ADA), which is responsible for breaking down toxic substances that would otherwise accumulate and damage the immune system. EXDENSUR® provides the missing ADA enzyme directly to your body through regular infusions. The medication is a pegylated form of the enzyme, meaning it's been modified to last longer in your system and work more effectively. By supplying this essential enzyme, EXDENSUR® helps clear toxic metabolites, allowing your immune system to recover and function more normally.
Conditions treated by this therapy
EXDENSUR® is FDA-approved for enzyme replacement therapy in patients with adenosine deaminase severe combined immune deficiency (ADA-SCID) who are not candidates for or did not have successful hematopoietic stem cell transplantation (HSCT).
EXDENSUR® Price
The cost of prescription medications can vary depending on your insurance coverage. If you're concerned about the price of your medication:
- Contact your insurance provider to understand your coverage
- Ask your doctor or pharmacist about lower-cost alternatives
- Check with the drug manufacturer about financial assistance programs
- Explore patient assistance options if you're uninsured or underinsured
Remember, many resources exist to help patients access necessary medications. Don't hesitate to ask for help if you're struggling with medication costs. No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities, contact a member of our Violet Health team.
What to Expect During EXDENSUR® Injection Therapy
EXDENSUR® is administered as an intramuscular (IM) injection, not an intravenous infusion. The dosing schedule is highly individualized based on your body weight, immune function, and response to therapy. Most patients receive injections weekly or multiple times per week as determined by their specialist.
When you arrive at our West Bloomfield location, you'll experience our calming, wellness-focused atmosphere. Our experienced team will:
- Review your current health status and any concerns
- Check your vital signs
- Administer the injection (typically in the thigh or upper arm)
- Monitor you for any immediate reactions
- Ensure your comfort throughout the brief procedure
The injection itself takes only a few minutes, though we'll monitor you for a period afterward to ensure you're feeling well before you leave.
Our team at Violet Infusions coordinates closely with your specialist to ensure seamless care and will help you stay on track with your regular treatment schedule.
EXDENSUR® Side Effects
As with any medication, EXDENSUR® may cause side effects. Being informed helps you know what to watch for and when to contact your healthcare team. Common Side Effects:
- Injection site reactions (pain, redness, swelling)
- Headache
- Cough
- Diarrhea
- Vomiting
- Fever
Although rare, serious side affects can occur. Please alert our clinical staff or seek medical attention immediately if you experience fever or signs of infection, unusual bruising or bleeding, allergic reaction or any new or concerning symptoms.
Our list may not include all possible side effects of EXDENSUR®
EXDENSUR® Injection Therapy at Violet Health
Your comfort during EXDENSUR® injection therapy at Violet Health is our priority. Our patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Plus, Violet Health’s evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.
Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.
Helpful Resources
Patient Forms
Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!
Meet our Infusion Specialists
Jalal Thwainey M.D.
Medical Director
Emilie Wojcik, N.P.
Director of Clinical Services
For Provider
Simplify patient referrals and offer advanced treatment options with our infusion partnership program.
For Patient
There may be a better way to manage your condition – explore infusion therapy.