OXLUMO® Infusion Therapy

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About OXLUMO® Therapy

OXLUMO® (lumasiran) is the first FDA-approved prescription medicine for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults. It belongs to a class of medications called RNA interference (RNAi) agents, which are sometimes referred to as "gene silencers."

Condition treated by this therapy

Primary hyperoxaluria is a rare inherited disorder characterised by the overproduction of oxalate. Oxalate can form calcium oxalate deposits, which can cause stones in the kidney and urinary tract as well as injury to other organs such as the heart, eyes, bones and skin.

OXLUMO® is indicated for the treatment of primary hyperoxaluria type 1 (PH1) to lower oxalate in urine and blood in children and adults.

OXLUMO® Price

The cost of prescription medications can vary depending on your insurance coverage. If you're concerned about the price of your medication:

Contact your insurance provider to understand your coverage
Ask your doctor or pharmacist about lower-cost alternatives
Check with the drug manufacturer about financial assistance programs
Explore patient assistance options if you're uninsured or underinsured

Remember, many resources exist to help patients access necessary medications. Don't hesitate to ask for help if you're struggling with medication costs. No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities, contact a member of our Violet Health team.

What to Expect During OXLUMO® Therapy

OXLUMO® will be administered by a trained healthcare provider as an injection under the skin (subcutaneous injection) in the abdomen, thighs, or upper arms. Dosing is based on weight.

Starting doses: The first 4 doses are taken a month apart. The first 3 doses are starting doses to help bring oxalate levels down. The 4th dose is the first ongoing dose. If a dose is delayed or missed, contact your doctor as soon as possible.
Ongoing dosing: Administered quarterly (every 3 months) or monthly depending on weight.

OXLUMO® Side Effects

The most common side effects of OXLUMO® are:

Injection site reactions (redness, swelling, pain, bruising, itching, and discoloration at the site of injection)
Abdominal pain
Special precuastions should be taken in presence of kidney disease and pregnancy

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

OXLUMO® Therapy at Violet Health

Your comfort during OXLUMO® therapy at Violet Health is our priority. Our patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Plus, Violet Health’s evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.

Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.

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Patient Forms

Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!