Our Therapies

YEZTUGO® Infusion Therapy

About YEZTUGO® Injection Therapy

YEZTUGO® (cabotegravir and rilipivirine) is a complete long-acting HIV treatment regimen that represents a significant advancement in HIV care. Unlike daily oral medications, YEZTUGO® is administered as monthly or every-other-month injections, offering a new level of convenience and freedom for people living with HIV.

Conditions treated by this therapy

Yeztugo® is FDA-approved as a complete regimen for the treatment of HIV-1 infection in adults who meet specific criteria:

Have achieved virologic suppression (undetectable viral load) on their current antiretroviral regimen
Have no history of treatment failure
Have no known resistance to cabotegravir or rilpivirine

YEZTUGO® Price

The cost of prescription medications can vary depending on your insurance coverage. If you're concerned about the price of your medication:

Contact your insurance provider to understand your coverage
Ask your doctor or pharmacist about lower-cost alternatives
Check with the drug manufacturer about financial assistance programs
Explore patient assistance options if you're uninsured or underinsured

Remember, many resources exist to help patients access necessary medications. Don't hesitate to ask for help if you're struggling with medication costs. No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities, contact a member of our Violet Health team.

What to Expect During YEZTUGO® Injection Therapy

Before starting YEZTUGO®, your provider will conduct comprehensive testing including confirmation of viral suppression (undetectable viral load), resistance testing to ensure the medications will be effective and an assessment of your medical history and any contradictions.

After an oral lead-in YEZTUGO® injections are given twice as an initiation dose with one last day of an oral lead-in. Then either a monthly dosing schedule or an every-other-month dosing schedule will be chosen for your treatment as indicated by your provider. Injections take only a few minutes.

After your appointment you can resume normal activities immediately.

YEZTUGO® Side Effects

As with any medication, YEZTUGO® may cause side effects. Being informed helps you know what to watch for and when to contact your healthcare team. Common Side Effects:

Injection site reactions (pain, redness, swelling)
Headache
Fever
Fatigue
Muscle or back pain
Rash
Nausea

Although rare, serious side affects can occur. Please alert our clinical staff or seek medical attention immediately if you experience fever or signs of infection, unusual bruising or bleeding, allergic reaction, signs of liver problems (yellowing skin or eyes, dark urine, severe abdominal pain), depression, mood swings, or any new or concerning symptoms.

Our list may not include all possible side effects of YEZTUGO®

YEZTUGO® Injection Therapy at Violet Health

Your comfort during YEZTUGO®® injection therapy at Violet Health is our priority. Our patients enjoy walk-up parking, complimentary entertainment and snacks, and a team of highly trained providers during each treatment. Plus, Violet Health’s evening and weekend hours and convenient city and rural locations make it easier to schedule your appointments.

Violet Health Infusion Centers provides infusion therapy for patients with rare, chronic, or complex conditions in a comfortable, patient-centered atmosphere.

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Helpful Resources

Patient Forms

Before you attend your first appointment at Violet Health, please make sure to review the documents below. Please contact us if you have any questions!